Researchers have developed a more accurate method for measuring BPA levels in humans and found that exposure to chemicals that destroy the endocrine system is much higher than expected.
The study provides the first evidence that measurements reported by regulators, including the US Food and Drug Administration, are inadequate and underestimate the 44-fold level of exposure.
This study raises serious concerns about whether we are careful enough about the safety of these chemicals.
Professor at Washington State University and author of the corresponding article. This number is that the conclusions that federal regulators have to regulate BPA may be based on inaccurate measurements.
BPA included in various plastics, including food and beverage containers. Animal studies show that it can affect the body’s hormones. fetal exposure to BPAass associated with problems related to growth, metabolism, behavior, fertility, and an even higher risk of cancer.
Despite this experimental evidence, the FDA has evaluated data from studies that measure BPA in human urine and found that human exposure to chemicals is very low and thus harmless.
This paper challenges this assumption and raises questions about other chemicals, including BPA substitution, which are also evaluated using indirect methods.
Hunt’s colleague, Roy Gerona, assistant professor at the University of California at San Francisco, has developed a direct method for measuring BPA that takes into account BPA metabolites, compounds that form when chemicals pass through the human body.
So far, most studies have had to use indirect methods to measure BPA metabolites, using a slug enzyme solution to convert metabolites back to BPA, which can then measured.
The new Gerona method can measure BPA metabolites without using an enzyme solution.
In this study, a research team consisting of Gerona, Hunt, and Fredrick from the University of Missouri Hall compared the two methods first with synthetic urine infused with BPA and then with 39 human samples. They found a much higher BPA level with the direct method, which was 44 times higher than the average reported in the National Health and Nutrition Examination Survey (NHANES).
The inconsistency between the two methods increases because exposure to BPA increases: the higher the exposure, the more previous methods ignored.
I hope that this research draws attention to the BPA measurement method and that other experts and laboratories look at and assess whatever happens.
The research team is conducting more experiments to measure BPA and other chemicals that can also be measured in this way. This category includes phenols in the environment, such as parabens, benzophenone, triclosan, which found in some cosmetics and soaps. and phthalates contained in many consumer products, including toys, food packaging, and personal care products.
BPA is still measured by NHANES, and it’s not the only endocrine-disrupting chemical measured this way, the researchers said. We hypothesize that if this applies to BPA, it will apply to all other chemicals that measured.