Copper-based nanomaterials can kill cancer cells in mice, An interdisciplinary team of scientists was able to kill tumor cells in mice with nanoscale copper compounds and immunotherapy. Cancer does not return after therapy.
Recent advances in cancer therapy have used their own immunity to fight cancer. But in some cases, immunotherapy failed. A team of biomedical researchers, physicists, and chemical engineers has found that tumors are sensitive to copper oxide nanoparticles, a combination of copper and oxygen, so now researchers found Copper-based nanomaterials can kill cancer cells in mice.
After swallowing, these nanoparticles dissolve and become toxic. By producing nanoparticles using iron oxide, researchers can control this process to eliminate cancer cells until healthy cells are affected.
As researchers expected, the cancer only returned after treatment with nanoparticles. So they combine nanoparticles with immunotherapy.
The combination of nanoparticles and immunotherapy makes the tumor completely disappear and acts as a vaccine against lung and colon cancer, both of which were examined in this study. To confirm their results, the researchers injected tumor cells back into the mice. These cells are immediately eliminated by the body’s immune system, which looks for new, similar cells to enter the body.
The authors state that the new technique can be used for about sixty percent of all cancers, because cancer cells are caused by mutations in the p53 gene. Examples include lung, breast, ovarian and colon cancer.
The key point is that the tumor has disappeared without using chemotherapy, which is usually associated with serious side effects. Chemotherapy drugs not only attack cancer cells, but also often damage healthy cells. For example, some of these drugs eliminate white blood cells and the immune system.
Nanomedicine grows in the United States and Asia, but Europe is still lagging behind. The challenges in this field are challenging because doctors and engineers often speak various languages. We need more interdisciplinary collaboration so we can better understand each other and build our knowledge.