The new synthesized mosquitoes that stop transmission of the dengue virus, An international team of scientists has synthesized mosquitoes that stop transmission of the dengue virus. The research team explained the details of the achievement of the Aedes aegypti mosquito, an insect that transmits dengue to humans.
The development marks the first technical approach to mosquitoes, targeting four known types of dengue and improving previous designs for individual strains. They then developed antibody “load” so that it becomes synthetic in female A. aegypti female mosquitoes that spread the dengue virus.
After the female mosquito draws blood, the antibody activates and states that it is the trigger, researchers say. the synthesized mosquitoes that stop transmission of the dengue virus.
Antibodies can inhibit the replication of the virus and prevent it from spreading in mosquitoes, thus preventing transmission to humans. This is a strong approach. Technical mosquitoes can be easily combined with reproductive systems, such as gene machines, which are based on CRISPR / CAS-9 technology and are able to spread antibodies against wild diseases that transmit the disease.
According to the World Health Organization, the dengue virus threatens millions of people in tropical and subtropical climates. In many countries in Asia and Latin America, severe dengue is a leading cause of serious illness and death in children. The Pan American Health Organization recently reported the highest number of dengue cases ever reported in America.
People with dengue fever who infect people with weak immune systems suffer from flu-like symptoms, including fever and severe rashes. In severe cases, life-threatening bleeding can occur. At present there is no specific treatment, so prevention and control depends on steps to stop the spread of the virus.
This development means that there may be a feasible genetic approach to fighting dengue virus in the future that can limit human suffering and death. This is the initial stage of the testing method for the simultaneous neutralization of dengue mosquitoes and various other viruses such as zika, yellow fever and chikungunya. said the researcher.
Mosquitoes have been given a bad reputation as the most deadly killers in the world because they are messenger substances that transmit diseases such as malaria, dengue fever, chikungunya, zika and yellow fever and endanger a total of 6.5 billion people worldwide.
This study shows that it is possible to immunize mosquitoes and prevent their ability to transmit dengue virus and possible pathogens carried by other mosquitoes.