Scientists found how cells sort and recycle their components, What can be reused and thrown away? Cells also face this difficult task. Researchers have now discovered a cell machine called FERARI that sorts the recyclable proteins used.
Recycling, reusing materials saves energy and resources. No wonder that nature also recycles.
Small organelles, called endosomes, separate the cell material provided into reusable material and waste. now the researchers foundhow cells sort and recycle their components.
Exactly how endosomes are sorted remains a mystery.
FERARI distributes recyclable molecules, mainly transporting proteins and receptors and reintroducing them into the cell cycle. In this way, valuable cell components do not have to be continuously reproduced, which saves not only energy but also time.
Endosomes are small vesicles that are membrane bound to animal and plant cells. During maturation, endosomes go through various stages in which they perform different tasks.
Early endosomes mainly absorb material, older endosomes sort recyclable materials, and end endomes remove residual waste that cannot be reused. how cells sort and recycle their components.
When sorting endosomes, researchers have proven that FERARI acts as a kind of distribution platform.
FERARI consists of various proteins and is responsible for ensuring that vesicles used for recycling are placed on endosome sequencing and can be loaded with reusable materials.
The feature of FERARI is that it coordinates both endosome fusion with recycled vesicles (kisses) and tearing of recycled vesicles after loading with loads (walking). The filled vesicles then carry their charge to the work site, the cell membrane.
Our work contradicts the current view that all recycled vesicles are cut off directly from endosomes, Researcher said.
If FERARI does not function properly, cell recycling is disrupted. Disruption in cellular transportation and recycling processes can cause various diseases, including cancer, metabolic and neurodegenerative diseases.