Natural compounds in vegetables help fight fatty liver disease, A new study by Research shows how natural compounds found in many famous and often consumed vegetables can also be used to combat fatty liver disease.
This study shows how indole can combat non-alcoholic fatty liver disease or NAFLD, a natural compound found in intestinal bacteria and cruciferous vegetables such as cabbage, cabbage, cauliflower and Brussels sprouts.
It is also investigating how these natural compounds can lead to new treatments or preventative measures for NAFLD. Natural compounds in vegetables help fight fatty liver disease.
Based on this research, we believe that healthy food with high indole production capacity is very important for the prevention of NAFLD and can improve the health of those affected, “said Chaodong Wu, MM .sc, PhD at Associate and Principal of Texas A&M AgriLife.
This is another example where changing your diet can help prevent or treat a disease and improve one’s well-being.
NAFLD occurs when the liver is mixed with fat, sometimes due to an unhealthy diet, such as excessive intake of saturated fat.
If not resolved properly, it can cause life-threatening liver disease, including cirrhosis or liver cancer.
Many different factors contribute to NAFLD. Fatty liver is seven to ten times more common in people who are overweight than the general population. In addition, obesity causes inflammation in the body. This inflammation is a macrophage, a type of white blood cell that usually fights infection. Natural compounds in vegetables help fight fatty liver disease.
This inflammation worsens liver damage in patients with liver disease.
Liver bacteria can also have positive or negative effects on the development of fatty liver disease. This bacterium produces many different compounds, one of which is indole. This amino acid tryptophan product has been classified by clinical nutritionists and nutritionists as an effective prevention and therapy for people with NAFLD.
The National Cancer Institute also notes the benefits of indole-3-carbinol in cruciferous vegetables, including their anti-inflammatory and carcinogenic properties.
This study investigates the effects of indole concentrations in humans, animal models and single cells to determine the effects of indole on liver inflammation and potential benefits for people with NAFLD. He examined the extent to which indole reduces non-alcoholic fatty liver disease, taking into account previous findings in intestinal bacteria, intestinal inflammation and inflammation of the liver.
This also includes studies on how indole increases fatty liver in animal models.
With 137 participants, the research team found that people with a higher body mass index tended to have lower levels of indole in their blood. In addition, the indole value for people who are overweight is significantly lower than those classified as lean.
And those who have lower levels of indole have higher levels of fat in their hearts.
This finding is likely to affect other ethnic groups, Li noted, although ethnicity can have an impact on intestinal populations and proper metabolite levels.
To further determine the effects of indole, the research team used animal models that received a low-fat diet as a control and a high-fat diet to simulate the effects of NAFLD.
The research team is also investigating how indole affects individual cells.
Researchers say that in addition to reducing the amount of fat in liver cells, indole also affects cells in the intestine that send molecular signals that suppress inflammation.
The relationship between the intestine and liver adds another layer of complex research to non-alcoholic fatty liver disease. Future research is needed to fully understand the role of indole, researchers say.
Foods with high capacity to produce indole or drugs that mimic their effects can be a new therapy for the treatment of NAFLD. Preventing the development and development of NAFLD can depend on a nutritional approach to ensure that intestinal microbes enable effective functioning of indole and other metabolites, the researchers said.
Future research is needed to find out how some diets can achieve this.