The research team studies how the virus forms its symmetrical shell, Viruses, small pathogens that can infect all types of life, have been well studied, but there are still many puzzles.
One of the puzzles is how the ball virus passes through energy barriers to form symmetrical shells.
Understanding the factors that contribute to virus accumulation can enable biomedical efforts to block replication and infection by viruses.
A better understanding of how important the nano-container shape of a virus projectile is to material scientists, and an important step in the development of a nano shell that can function as a vehicle to deliver drugs to specific targets in the body.
An understanding of the combined effects of elastic energy, interactions between genomes and proteins and protein concentrations in viral aggregates is a breakthrough in our work.
As the simplest physical object in biology, a virus consists of a protein coat called a capsid that protects its nucleic acid genome – RNA or DNA.
Viruses can be seen as movable containers with RNA or DNA that enter their genetic material into living cells.
They then took on the cell’s reproductive machinery to reproduce their own genome and capsid.
Formation of capsid is one of the most important steps in the process of viral infection. The capsid may have a cylindrical or conical shape, but more often it takes an icosahedral structure, like a soccer ball. The research team studies how the virus forms its symmetrical shell.
Icosahedron is a geometric structure with 12 vertices, 20 surfaces and 30 sides.
Official soccer is a kind of icosahedron called the crossed icosahedron. It has 32 plates cut into 20 hexagons and 12 pentagons, pentagons separated by hexagons.
The composition of viruses is not well understood because viruses are very small, measured in nanometers, nanometers are one millionth of a meter.
Connections are also very fast, usually in milliseconds, milliseconds are one thousandth of a second. Theoretical and simulation work is needed to understand how viruses grow. The research team studies how the virus forms its symmetrical shell.
The new work found that the elastic properties of capsid proteins and the interesting interactions between them go hand in hand to form a very symmetrical configuration that is very stable to energy.
This virus capsids can be used as a nano container to transport drugs as a charge to certain destinations. According to researchers, understanding the factors that affect the stability of the structure of the terminal virus can improve control of the drug administration process.