Medical researcher wants to help premature babies breathe more easily, While the practice of oxygen titration to awaken newborns with difficulties has yielded better results.
There is disagreement in the medical community regarding the concentration of oxygen that must be given to premature babies born before the 29th week of pregnancy.
University of Alberta neonatologist Georg Schmolzer says the complication of this knowledge gap is that, until recently, researchers did not even agree on optimal oxygen concentrations to revive healthy babies.
When I started practicing in the early 2000s, it was normal to give your baby 100% oxygen so that the baby can “whiten” as soon as possible because the baby turns blue because the uterus has a low oxygen environment. Medical researcher wants to help premature babies breathe more easily.
Although 100 percent oxygen makes babies pink faster, the researchers found that leukemia and mortality were lower when babies were resuscitated with normal air containing 21 percent oxygen.
They found that administering 100% oxygen could actually prevent the baby from breathing at birth and cause apnea for a short time, the researchers said. Medical researcher wants to help premature babies breathe more easily.
Schmolzer explains that the lungs do not fully develop at 29 weeks of gestation or earlier, and babies often experience breathing problems at birth.
We started at 100 percent, but knowing that 100% isn’t perfect for premature babies, many experts around the world suggest that we might have to give less, researchers say.
He discovered that there were a number of problems related to the presence of too much oxygen in the system.
Once in the body, oxygen atoms are split into free radicals which are believed to play a role in many diseases, including chronic lung disease and retinopathy in premature babies, a condition caused by abnormal blood vessel development in the retina of premature babies. can cause blindness. Medical researcher wants to help premature babies breathe more easily.
The body fights against free radical induced cells by using less antioxidants in premature babies. Increasing oxygen concentration can also cause brain damage.
However, it turns out that only using air to revive premature babies results in higher mortality.
To determine the exact oxygen concentration needed for resuscitation of premature infants, Schmolzer and his international research team received $ 2.2 million from the Canadian Institutes of Health.
The researchers will compare the results after 18 to 24 months in preterm infants born between 23 and 28 weeks of preterm infants who are given 30 percent or 60 percent oxygen.
Researchers say: We expect 60% oxygen to improve long-term outcomes, including (lower) death and cerebral palsy, fewer babies with vision problems, fewer babies with hearing loss, fewer babies who have major developmental delays